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High-resolution crystal structure of the human CB1 cannabinoid receptor

The human cannabinoid G protein-coupled receptors (GPCRs) CB1 and CB2 mediate the functional responses to the endocannabinoids anandamide and 2-arachidonyl glycerol (2-AG), as well as the widely consumed plant (phyto)cannabinoid Δ(9)-tetrahydrocannabinol (THC)(1). The cannabinoid receptors have been...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Shao, Zhenhua, Yin, Jie, Chapman, Karen, Grzemska, Magdalena, Clark, Lindsay, Wang, Junmei, Rosenbaum, Daniel M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433929/
https://ncbi.nlm.nih.gov/pubmed/27851727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20613
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