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Crystal structure of the human NK(1) tachykinin receptor
The NK(1) tachykinin G-protein–coupled receptor (GPCR) binds substance P, the first neuropeptide to be discovered in mammals. Through activation of NK(1)R, substance P modulates a wide variety of physiological and disease processes including nociception, inflammation, and depression. Human NK(1)R (h...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6310836/ https://ncbi.nlm.nih.gov/pubmed/30538204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812717115 |
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