Crystal structure of the human NK(1) tachykinin receptor

The NK(1) tachykinin G-protein–coupled receptor (GPCR) binds substance P, the first neuropeptide to be discovered in mammals. Through activation of NK(1)R, substance P modulates a wide variety of physiological and disease processes including nociception, inflammation, and depression. Human NK(1)R (h...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Yin, Jie, Chapman, Karen, Clark, Lindsay D., Shao, Zhenhua, Borek, Dominika, Xu, Qingping, Wang, Junmei, Rosenbaum, Daniel M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310836/
https://ncbi.nlm.nih.gov/pubmed/30538204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812717115
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