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Protocol for crystal structure determination of the antagonist-bound human cannabinoid receptor CB2

Human cannabinoid receptor CB2 plays an important role in the immune system and is an attractive therapeutic target for pain and for inflammatory and neurodegenerative diseases. However, the structural basis of CB2 agonist selectivity is still elusive. Here, we describe a detailed protocol for the d...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:STAR Protoc
Hauptverfasser: Shen, Ling, Li, Xiaoting, Liu, Junlin, Liu, Kaiwen, Liu, Zhi-Jie, Hua, Tian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192724/
https://ncbi.nlm.nih.gov/pubmed/34151302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100584
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