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Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase
Movement of the transcription machinery along a template alters DNA topology resulting in the accumulation of supercoils in DNA. The positive supercoils generated ahead of transcribing RNA polymerase (RNAP) and the negative supercoils accumulating behind impose severe topological constraints impedin...
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| 出版年: | PLoS Genet |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5433769/ https://ncbi.nlm.nih.gov/pubmed/28463980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006754 |
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