Cargando...
Targeting Mycobacterium tuberculosis Topoisomerase I by Small-Molecule Inhibitors
We describe inhibition of Mycobacterium tuberculosis topoisomerase I (MttopoI), an essential mycobacterial enzyme, by two related compounds, imipramine and norclomipramine, of which imipramine is clinically used as an antidepressant. These molecules showed growth inhibition of both Mycobacterium sme...
Gardado en:
| Publicado en: | Antimicrob Agents Chemother |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2015
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4325804/ https://ncbi.nlm.nih.gov/pubmed/25534741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04516-14 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|