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Autoregulation of topoisomerase I expression by supercoiling sensitive transcription

The opposing catalytic activities of topoisomerase I (TopoI/relaxase) and DNA gyrase (supercoiling enzyme) ensure homeostatic maintenance of bacterial chromosome supercoiling. Earlier studies in Escherichia coli suggested that the alteration in DNA supercoiling affects the DNA gyrase and TopoI expre...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Ahmed, Wareed, Menon, Shruti, D. N. B. Karthik, Pullela V., Nagaraja, Valakunja
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770202/
https://ncbi.nlm.nih.gov/pubmed/26496944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1088
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