Autoregulation of topoisomerase I expression by supercoiling sensitive transcription

The opposing catalytic activities of topoisomerase I (TopoI/relaxase) and DNA gyrase (supercoiling enzyme) ensure homeostatic maintenance of bacterial chromosome supercoiling. Earlier studies in Escherichia coli suggested that the alteration in DNA supercoiling affects the DNA gyrase and TopoI expre...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Ahmed, Wareed, Menon, Shruti, D. N. B. Karthik, Pullela V., Nagaraja, Valakunja
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770202/
https://ncbi.nlm.nih.gov/pubmed/26496944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1088
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