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Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase

Movement of the transcription machinery along a template alters DNA topology resulting in the accumulation of supercoils in DNA. The positive supercoils generated ahead of transcribing RNA polymerase (RNAP) and the negative supercoils accumulating behind impose severe topological constraints impedin...

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Vydáno v:PLoS Genet
Hlavní autoři: Ahmed, Wareed, Sala, Claudia, Hegde, Shubhada R., Jha, Rajiv Kumar, Cole, Stewart T., Nagaraja, Valakunja
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433769/
https://ncbi.nlm.nih.gov/pubmed/28463980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006754
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