Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer

Gallbladder cancer (GBC) is a lethal cancer with poor prognosis associated with high invasiveness and poor response to chemotherapy and radiotherapy. New therapeutic approaches are urgently needed in order to improve survival and response rates of GBC patients. We screened 130 small molecule inhibit...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Weber, Helga, Valbuena, José R., Barbhuiya, Mustafa A., Stein, Stefan, Kunkel, Hana, García, Patricia, Bizama, Carolina, Riquelme, Ismael, Espinoza, Jaime A., Kurtz, Stephen E., Tyner, Jeffrey W., Calderon, Juan Francisco, Corvalán, Alejandro H., Grez, Manuel, Pandey, Akhilesh, Leal-Rojas, Pamela, Roa, Juan C.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432248/
https://ncbi.nlm.nih.gov/pubmed/28412732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15410
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