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MEK inhibition potentiates the activity of Hsp90 inhibitor 17-AAG against pancreatic cancer cells
The Ras/Raf/MEK/ERK signaling has been implicated in uncontrolled cell proliferation and tumor progression in pancreatic cancer. The purpose of this study is to evaluate the antitumor activity of MEK inhibitor U0126 in combination with Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG)...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992603/ https://ncbi.nlm.nih.gov/pubmed/20669973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900321a |
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