Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice

Gallbladder cancer (GBC) is a highly malignant tumor characterized by a poor response to chemotherapy and radiotherapy. We evaluated the in vitro and in vivo antitumor efficacy of mTOR inhibitors, rapamycin and WYE-354. In vitro assays showed WYE-354 significantly reduced cell viability, migration a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Weber, Helga, Leal, Pamela, Stein, Stefan, Kunkel, Hana, García, Patricia, Bizama, Carolina, Espinoza, Jaime A., Riquelme, Ismael, Nervi, Bruno, Araya, Juan C., Grez, Manuel, Roa, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741647/
https://ncbi.nlm.nih.gov/pubmed/26397134
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