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ALOX5 exhibits anti-tumor and drug-sensitizing effects in MLL-rearranged leukemia
MLL-rearranged acute myeloid leukemia (AML) remains a fatal disease with a high rate of relapse and therapeutic failure due to chemotherapy resistance. In analysis of our Affymetrix microarray profiling and chromatin immunoprecipitation (ChIP) assays, we found that ALOX5 is especially down-regulated...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431828/ https://ncbi.nlm.nih.gov/pubmed/28500307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01913-y |
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