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Common sequence variants affect molecular function more than rare variants?
Any two unrelated individuals differ by about 10,000 single amino acid variants (SAVs). Do these impact molecular function? Experimental answers cannot answer comprehensively, while state-of-the-art prediction methods can. We predicted the functional impacts of SAVs within human and for variants bet...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431670/ https://ncbi.nlm.nih.gov/pubmed/28487536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01054-2 |
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