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Variant effect predictions capture some aspects of deep mutational scanning experiments

BACKGROUND: Deep mutational scanning (DMS) studies exploit the mutational landscape of sequence variation by systematically and comprehensively assaying the effect of single amino acid variants (SAVs; also referred to as missense mutations, or non-synonymous Single Nucleotide Variants – missense SNV...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Reeb, Jonas, Wirth, Theresa, Rost, Burkhard
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077003/
https://ncbi.nlm.nih.gov/pubmed/32183714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3439-4
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