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Better prediction of functional effects for sequence variants

Elucidating the effects of naturally occurring genetic variation is one of the major challenges for personalized health and personalized medicine. Here, we introduce SNAP2, a novel neural network based classifier that improves over the state-of-the-art in distinguishing between effect and neutral va...

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Vydáno v:BMC Genomics
Hlavní autoři: Hecht, Maximilian, Bromberg, Yana, Rost, Burkhard
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480835/
https://ncbi.nlm.nih.gov/pubmed/26110438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S8-S1
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