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Better prediction of functional effects for sequence variants

Elucidating the effects of naturally occurring genetic variation is one of the major challenges for personalized health and personalized medicine. Here, we introduce SNAP2, a novel neural network based classifier that improves over the state-of-the-art in distinguishing between effect and neutral va...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Hecht, Maximilian, Bromberg, Yana, Rost, Burkhard
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480835/
https://ncbi.nlm.nih.gov/pubmed/26110438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S8-S1
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