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Better prediction of functional effects for sequence variants

Elucidating the effects of naturally occurring genetic variation is one of the major challenges for personalized health and personalized medicine. Here, we introduce SNAP2, a novel neural network based classifier that improves over the state-of-the-art in distinguishing between effect and neutral va...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Hecht, Maximilian, Bromberg, Yana, Rost, Burkhard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480835/
https://ncbi.nlm.nih.gov/pubmed/26110438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S8-S1
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