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Protein Phosphatase 2A (PP2A) Regulates EG5 to Control Mitotic Progression
EG5 (KIF11) is a member of the kinesin-like protein family involved in centrosome separation and bipolar spindle formation. When a cell enters mitosis, CDK1 phosphorylates EG5 at Thr926 and promotes EG5 localization on the mitotic spindle which drives bipolar spindle formation. EG5 provides power fo...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431654/ https://ncbi.nlm.nih.gov/pubmed/28487562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01915-w |
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