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Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression

During cell division, progression through mitosis is driven by a protein phosphorylation wave. This wave namely depends on an activation-inactivation cycle of cyclin B-dependent kinase (Cdk) 1 while activities of major protein phosphatases, like PP1 and PP2A, appear directly or indirectly repressed...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Della Monica, Rosa, Visconti, Roberta, Cervone, Nando, Serpico, Angela Flavia, Grieco, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749544/
https://ncbi.nlm.nih.gov/pubmed/26653855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10399
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