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A PP1/PP2A phosphatase relay controls mitotic progression

The widespread reorganisation of cellular architecture in mitosis is achieved through extensive protein phosphorylation, driven by the coordinated activation of a mitotic kinase network and repression of counteracting phosphatases. Phosphatase activity must subsequently be restored to promote mitoti...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Grallert, Agnes, Boke, Elvan, Hagting, Anja, Hodgson, Ben, Connolly, Yvonne, Griffiths, John. R., Smith, Duncan L., Pines, Jonathon, Hagan, Iain M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338534/
https://ncbi.nlm.nih.gov/pubmed/25487150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14019
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