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Mitotic regulation of the human anaphase-promoting complex by phosphorylation
The anaphase-promoting complex (APC) or cyclosome is a ubiquitin ligase that initiates anaphase and mitotic exit. APC activation is thought to depend on APC phosphorylation and Cdc20 binding. We have identified 43 phospho-sites on APC of which at least 34 are mitosis specific. Of these, 32 sites are...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC291822/ https://ncbi.nlm.nih.gov/pubmed/14657031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg627 |
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