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Mitotic regulation of the human anaphase-promoting complex by phosphorylation

The anaphase-promoting complex (APC) or cyclosome is a ubiquitin ligase that initiates anaphase and mitotic exit. APC activation is thought to depend on APC phosphorylation and Cdc20 binding. We have identified 43 phospho-sites on APC of which at least 34 are mitosis specific. Of these, 32 sites are...

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Hlavní autoři: Kraft, Claudine, Herzog, Franz, Gieffers, Christian, Mechtler, Karl, Hagting, Anja, Pines, Jonathon, Peters, Jan-Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC291822/
https://ncbi.nlm.nih.gov/pubmed/14657031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg627
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