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Mitotic regulation of the human anaphase-promoting complex by phosphorylation

The anaphase-promoting complex (APC) or cyclosome is a ubiquitin ligase that initiates anaphase and mitotic exit. APC activation is thought to depend on APC phosphorylation and Cdc20 binding. We have identified 43 phospho-sites on APC of which at least 34 are mitosis specific. Of these, 32 sites are...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Kraft, Claudine, Herzog, Franz, Gieffers, Christian, Mechtler, Karl, Hagting, Anja, Pines, Jonathon, Peters, Jan-Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657031/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg627
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