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Control of mitotic transitions by the anaphase-promoting complex.

Proteolysis controls key transitions at several points in the cell cycle. In mitosis, the activation of a large ubiquitin-protein ligase, the anaphase-promoting complex (APC), is required for anaphase initiation and for exit from mitosis. We show that APC is under complex control by a network of reg...

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Main Authors: Fang, G, Yu, H, Kirschner, M W
格式: Artigo
語言:Inglês
出版: 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1692672/
https://ncbi.nlm.nih.gov/pubmed/10582244
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