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Anaphase-Promoting Complex/Cyclosome Controls the Stability of TPX2 during Mitotic Exit
TPX2, a microtubule-associated protein, is required downstream of Ran-GTP to induce spindle assembly. TPX2 activity appears to be tightly regulated during the cell cycle, and we report here one molecular mechanism for this regulation. We found that TPX2 protein levels are cell cycle regulated, peaki...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1291225/ https://ncbi.nlm.nih.gov/pubmed/16287863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10516-10527.2005 |
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