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A role of human RNase P subunits, Rpp29 and Rpp21, in homology directed-repair of double-strand breaks

DNA damage response (DDR) is needed to repair damaged DNA for genomic integrity preservation. Defective DDR causes accumulation of deleterious mutations and DNA lesions that can lead to genomic instabilities and carcinogenesis. Identifying new players in the DDR, therefore, is essential to advance t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Abu-Zhayia, Enas R., Khoury-Haddad, Hanan, Guttmann-Raviv, Noga, Serruya, Raphael, Jarrous, Nayef, Ayoub, Nabieh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430778/
https://ncbi.nlm.nih.gov/pubmed/28432356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01185-6
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