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PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair
Members of the lysine (K)-specific demethylase 4 (KDM4) A–D family of histone demethylases are dysregulated in several types of cancer. Here, we reveal a previously unrecognized role of KDM4D in the DNA damage response (DDR). We show that the C-terminal region of KDM4D mediates its rapid recruitment...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932863/ https://ncbi.nlm.nih.gov/pubmed/24550317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317585111 |
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