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NELF‐E is recruited to DNA double‐strand break sites to promote transcriptional repression and repair

Double‐strand breaks (DSBs) trigger rapid and transient transcription pause to prevent collisions between repair and transcription machineries at damage sites. Little is known about the mechanisms that ensure transcriptional block after DNA damage. Here, we reveal a novel role of the negative elonga...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Awwad, Samah W, Abu‐Zhayia, Enas R, Guttmann‐Raviv, Noga, Ayoub, Nabieh
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412775/
https://ncbi.nlm.nih.gov/pubmed/28336775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643191
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