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NELF‐E is recruited to DNA double‐strand break sites to promote transcriptional repression and repair

Double‐strand breaks (DSBs) trigger rapid and transient transcription pause to prevent collisions between repair and transcription machineries at damage sites. Little is known about the mechanisms that ensure transcriptional block after DNA damage. Here, we reveal a novel role of the negative elonga...

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Podrobná bibliografie
Vydáno v:EMBO Rep
Hlavní autoři: Awwad, Samah W, Abu‐Zhayia, Enas R, Guttmann‐Raviv, Noga, Ayoub, Nabieh
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412775/
https://ncbi.nlm.nih.gov/pubmed/28336775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643191
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