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A role of human RNase P subunits, Rpp29 and Rpp21, in homology directed-repair of double-strand breaks
DNA damage response (DDR) is needed to repair damaged DNA for genomic integrity preservation. Defective DDR causes accumulation of deleterious mutations and DNA lesions that can lead to genomic instabilities and carcinogenesis. Identifying new players in the DDR, therefore, is essential to advance t...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5430778/ https://ncbi.nlm.nih.gov/pubmed/28432356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01185-6 |
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