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A role of human RNase P subunits, Rpp29 and Rpp21, in homology directed-repair of double-strand breaks

DNA damage response (DDR) is needed to repair damaged DNA for genomic integrity preservation. Defective DDR causes accumulation of deleterious mutations and DNA lesions that can lead to genomic instabilities and carcinogenesis. Identifying new players in the DDR, therefore, is essential to advance t...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Abu-Zhayia, Enas R., Khoury-Haddad, Hanan, Guttmann-Raviv, Noga, Serruya, Raphael, Jarrous, Nayef, Ayoub, Nabieh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430778/
https://ncbi.nlm.nih.gov/pubmed/28432356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01185-6
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