A role of human RNase P subunits, Rpp29 and Rpp21, in homology directed-repair of double-strand breaks

DNA damage response (DDR) is needed to repair damaged DNA for genomic integrity preservation. Defective DDR causes accumulation of deleterious mutations and DNA lesions that can lead to genomic instabilities and carcinogenesis. Identifying new players in the DDR, therefore, is essential to advance t...

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Udgivet i:Sci Rep
Main Authors: Abu-Zhayia, Enas R., Khoury-Haddad, Hanan, Guttmann-Raviv, Noga, Serruya, Raphael, Jarrous, Nayef, Ayoub, Nabieh
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430778/
https://ncbi.nlm.nih.gov/pubmed/28432356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01185-6
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