IL-37 Suppresses MyD88-mediated Inflammatory Responses in Human Aortic Valve Interstitial Cells

Calcific aortic valve disease (CAVD) is common among the elderly, and aortic valve interstitial cells (AVICs) exhibit unique inflammatory and osteogenic responses to proinflammatory stimulation, which plays an important role in valvular fibrosis and calcification. Thus, suppression of AVIC proinflam...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Med
Hauptverfasser: Zhan, Qiong, Zeng, Qingchun, Song, Rui, Zhai, Yufeng, Xu, Dingli, Fullerton, David A, Dinarello, Charles A, Meng, Xianzhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Feinstein Institute for Medical Research 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429883/
https://ncbi.nlm.nih.gov/pubmed/28362018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2017.00022
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