IL-37 Suppresses MyD88-mediated Inflammatory Responses in Human Aortic Valve Interstitial Cells

Calcific aortic valve disease (CAVD) is common among the elderly, and aortic valve interstitial cells (AVICs) exhibit unique inflammatory and osteogenic responses to proinflammatory stimulation, which plays an important role in valvular fibrosis and calcification. Thus, suppression of AVIC proinflam...

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Foilsithe in:Mol Med
Main Authors: Zhan, Qiong, Zeng, Qingchun, Song, Rui, Zhai, Yufeng, Xu, Dingli, Fullerton, David A, Dinarello, Charles A, Meng, Xianzhong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Feinstein Institute for Medical Research 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429883/
https://ncbi.nlm.nih.gov/pubmed/28362018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2017.00022
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