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Structural Insight into the Specific DNA Template Binding to DnaG primase in Bacteria

Bacterial primase initiates the repeated synthesis of short RNA primers that are extended by DNA polymerase to synthesize Okazaki fragments on the lagging strand at replication forks. It remains unclear how the enzyme recognizes specific initiation sites. In this study, the DnaG primase from Bacillu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Yingqin, Luo, Hao, Liu, Zhongchuan, Yang, Mu, Pang, Xiaoyun, Sun, Fei, Wang, Ganggang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429622/
https://ncbi.nlm.nih.gov/pubmed/28386108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00767-8
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