Evaluation of DNA Primase DnaG as a Potential Target for Antibiotics

Mycobacteria contain genes for several DNA-dependent RNA primases, including dnaG, which encodes an essential replication enzyme that has been proposed as a target for antituberculosis compounds. An in silico analysis revealed that mycobacteria also possess archaeo-eukaryotic superfamily primases (A...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kuron, Aneta, Korycka-Machala, Malgorzata, Brzostek, Anna, Nowosielski, Marcin, Doherty, Aidan, Dziadek, Bozena, Dziadek, Jaroslaw
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Mechanisms of Action: Physiological Effects
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957862/
https://ncbi.nlm.nih.gov/pubmed/24379196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01721-13
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