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DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria

Prokaryotic Ligase D is a conserved DNA repair apparatus processing DNA double-strand breaks in stationary phase. An orthologous Ligase C (LigC) complex also co-exists in many bacterial species but its function is unknown. Here we show that the LigC complex interacts with core BER enzymes in vivo an...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Płociński, Przemysław, Brissett, Nigel C., Bianchi, Julie, Brzostek, Anna, Korycka-Machała, Małgorzata, Dziembowski, Andrzej, Dziadek, Jarosław, Doherty, Aidan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663958/
https://ncbi.nlm.nih.gov/pubmed/29089537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01365-y
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