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PolDIP2 interacts with human PrimPol and enhances its DNA polymerase activities

Translesion synthesis (TLS) employs specialized DNA polymerases to bypass replication fork stalling lesions. PrimPol was recently identified as a TLS primase and polymerase involved in DNA damage tolerance. Here, we identify a novel PrimPol binding partner, PolDIP2, and describe how it regulates Pri...

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Pubblicato in:Nucleic Acids Res
Autori principali: Guilliam, Thomas A., Bailey, Laura J., Brissett, Nigel C., Doherty, Aidan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838387/
https://ncbi.nlm.nih.gov/pubmed/26984527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw175
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