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Human PrimPol mutation associated with high myopia has a DNA replication defect
PrimPol is a primase-polymerase found in humans, and other eukaryotes, involved in bypassing lesions encountered during DNA replication. PrimPol employs both translesion synthesis and repriming mechanisms to facilitate lesion bypass by the replisome. PrimPol has been reported to be a potential susce...
में बचाया:
| में प्रकाशित: | Nucleic Acids Res |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231748/ https://ncbi.nlm.nih.gov/pubmed/25262353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku879 |
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