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Mitochondrial DNA replication: a PrimPol perspective

PrimPol, (primase–polymerase), the most recently identified eukaryotic polymerase, has roles in both nuclear and mitochondrial DNA maintenance. PrimPol is capable of acting as a DNA polymerase, with the ability to extend primers and also bypass a variety of oxidative and photolesions. In addition, P...

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Bibliographic Details
Published in:Biochem Soc Trans
Main Authors: Bailey, Laura J., Doherty, Aidan J.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390496/
https://ncbi.nlm.nih.gov/pubmed/28408491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160162
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