Loading...

PrimPol is required for the maintenance of efficient nuclear and mitochondrial DNA replication in human cells

Eukaryotic Primase-Polymerase (PrimPol) is an enzyme that maintains efficient DNA duplication by repriming replication restart downstream of replicase stalling lesions and structures. To elucidate the cellular requirements for PrimPol in human cells, we generated PrimPol-deleted cell lines and show...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Bailey, Laura J, Bianchi, Julie, Doherty, Aidan J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486543/
https://ncbi.nlm.nih.gov/pubmed/30715459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz056
Tags: Add Tag
No Tags, Be the first to tag this record!