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PrimPol is required for the maintenance of efficient nuclear and mitochondrial DNA replication in human cells
Eukaryotic Primase-Polymerase (PrimPol) is an enzyme that maintains efficient DNA duplication by repriming replication restart downstream of replicase stalling lesions and structures. To elucidate the cellular requirements for PrimPol in human cells, we generated PrimPol-deleted cell lines and show...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486543/ https://ncbi.nlm.nih.gov/pubmed/30715459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz056 |
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