Molecular basis for PrimPol recruitment to replication forks by RPA

DNA damage and secondary structures can stall the replication machinery. Cells possess numerous tolerance mechanisms to complete genome duplication in the presence of such impediments. In addition to translesion synthesis (TLS) polymerases, most eukaryotic cells contain a multifunctional replicative...

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Publicat a:Nat Commun
Autors principals: Guilliam, Thomas A., Brissett, Nigel C., Ehlinger, Aaron, Keen, Benjamin A., Kolesar, Peter, Taylor, Elaine M., Bailey, Laura J., Lindsay, Howard D., Chazin, Walter J., Doherty, Aidan J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457501/
https://ncbi.nlm.nih.gov/pubmed/28534480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15222
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