Molecular basis for PrimPol recruitment to replication forks by RPA

DNA damage and secondary structures can stall the replication machinery. Cells possess numerous tolerance mechanisms to complete genome duplication in the presence of such impediments. In addition to translesion synthesis (TLS) polymerases, most eukaryotic cells contain a multifunctional replicative...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Guilliam, Thomas A., Brissett, Nigel C., Ehlinger, Aaron, Keen, Benjamin A., Kolesar, Peter, Taylor, Elaine M., Bailey, Laura J., Lindsay, Howard D., Chazin, Walter J., Doherty, Aidan J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457501/
https://ncbi.nlm.nih.gov/pubmed/28534480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15222
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