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Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG
Due to the rise in drug resistance in tuberculosis combined with the global spread of its causative pathogen, Mycobacterium tuberculosis (Mtb), innovative anti-mycobacterial agents are urgently needed. Recently, we developed a novel primase-pyrophosphatase assay and used it to discover inhibitors of...
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| Publicado no: | J Antibiot (Tokyo) |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5687077/ https://ncbi.nlm.nih.gov/pubmed/25248725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2014.131 |
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