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Structural Insight into the Specific DNA Template Binding to DnaG primase in Bacteria

Bacterial primase initiates the repeated synthesis of short RNA primers that are extended by DNA polymerase to synthesize Okazaki fragments on the lagging strand at replication forks. It remains unclear how the enzyme recognizes specific initiation sites. In this study, the DnaG primase from Bacillu...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zhou, Yingqin, Luo, Hao, Liu, Zhongchuan, Yang, Mu, Pang, Xiaoyun, Sun, Fei, Wang, Ganggang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429622/
https://ncbi.nlm.nih.gov/pubmed/28386108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00767-8
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