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DnaG Primase—A Target for the Development of Novel Antibacterial Agents

The bacterial primase—an essential component in the replisome—is a promising but underexploited target for novel antibiotic drugs. Bacterial primases have a markedly different structure than the human primase. Inhibition of primase activity is expected to selectively halt bacterial DNA replication....

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Ilic, Stefan, Cohen, Shira, Singh, Meenakshi, Tam, Benjamin, Dayan, Adi, Akabayov, Barak
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163395/
https://ncbi.nlm.nih.gov/pubmed/30104489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics7030072
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