Rationally Designed TLR4 Ligands for Vaccine Adjuvant Discovery

Adjuvant properties of bacterial cell wall components like MPLA (monophosphoryl lipid A) are well described and have gained FDA approval for use in vaccines such as Cervarix. MPLA is the product of chemically modified lipooligosaccharide (LOS), altered to diminish toxic proinflammatory effects while...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:mBio
Main Authors: Gregg, Kelsey A., Harberts, Erin, Gardner, Francesca M., Pelletier, Mark R., Cayatte, Corinne, Yu, Li, McCarthy, Michael P., Marshall, Jason D., Ernst, Robert K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424205/
https://ncbi.nlm.nih.gov/pubmed/28487429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00492-17
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados