In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant

Most infections occur in early life, prompting development of novel adjuvanted vaccines to protect newborns and infants. Several Toll-like receptor (TLR) agonists (TLRAs) are components of licensed vaccine formulations or are in development as candidate adjuvants. However, the type and magnitude of...

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Publicado no:Cytokine
Main Authors: Van Haren, Simon D., Ganapathi, Lakshmi, Bergelson, Ilana, Dowling, David J., Banks, Michaela, Samuels, Ronald C., Reed, Steven G., Marshall, Jason D., Levy, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906944/
https://ncbi.nlm.nih.gov/pubmed/27081760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2016.04.001
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