Distinct Toll-like receptor-mediated cytokine production and immunoglobulin secretion in human newborn naïve B cells

Neonatal innate immunity is distinct from that of adults, which may contribute to increased susceptibility to infection and limit vaccine responses. B cells play critical roles in protection from infection and detect PAMPs via TLRs, that, when co-activated with CD40, can drive B cell proliferation a...

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Bibliographic Details
Published in:Innate Immun
Main Authors: Pettengill, Matthew A, van Haren, Simon D, Li, Ning, Dowling, David J, Bergelson, Ilana, Jans, Jop, Ferwerda, Gerben, Levy, Ofer
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963298/
https://ncbi.nlm.nih.gov/pubmed/27252169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425916651985
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