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Distinct Toll-like receptor-mediated cytokine production and immunoglobulin secretion in human newborn naïve B cells
Neonatal innate immunity is distinct from that of adults, which may contribute to increased susceptibility to infection and limit vaccine responses. B cells play critical roles in protection from infection and detect PAMPs via TLRs, that, when co-activated with CD40, can drive B cell proliferation a...
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| Pubblicato in: | Innate Immun |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4963298/ https://ncbi.nlm.nih.gov/pubmed/27252169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425916651985 |
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