A lipid A-based TLR4 mimetic effectively adjuvants a Yersinia pestis rF-V1 subunit vaccine in a murine challenge model

Vaccination can significantly reduce worldwide morbidity and mortality to infectious diseases, thereby reducing the health burden as a result of microbial infections. Effective vaccines contain three components: a delivery system, an antigenic component of the pathogen, and an adjuvant. With the gro...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Gregg, Kelsey A., Harberts, Erin, Gardner, Francesca M., Pelletier, Mark R., Cayatte, Corinne, Yu, Li, McCarthy, Michael P., Marshall, Jason D., Ernst, Robert K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057149/
https://ncbi.nlm.nih.gov/pubmed/29861179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.05.101
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