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Live cell imaging of low- and non-repetitive chromosome loci using CRISPR-Cas9
Imaging chromatin dynamics is crucial to understand genome organization and its role in transcriptional regulation. Recently, the RNA-guidable feature of CRISPR-Cas9 has been utilized for imaging of chromatin within live cells. However, these methods are mostly applicable to highly repetitive region...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5424063/ https://ncbi.nlm.nih.gov/pubmed/28290446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14725 |
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