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Cas9-chromatin binding information enables more accurate CRISPR off-target prediction

The CRISPR system has become a powerful biological tool with a wide range of applications. However, improving targeting specificity and accurately predicting potential off-targets remains a significant goal. Here, we introduce a web-based CRISPR/Cas9 Off-target Prediction and Identification Tool (CR...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Singh, Ritambhara, Kuscu, Cem, Quinlan, Aaron, Qi, Yanjun, Adli, Mazhar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605288/
https://ncbi.nlm.nih.gov/pubmed/26032770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv575
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