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A ribonucleotide reductase inhibitor with deoxyribonucleoside‐reversible cytotoxicity
Ribonucleotide Reductase (RNR) is the sole enzyme that catalyzes the reduction of ribonucleotides into deoxyribonucleotides. Even though RNR is a recognized target for antiproliferative molecules, and the main target of the approved drug hydroxyurea, few new leads targeted to this enzyme have been d...
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| Publié dans: | Mol Oncol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5423217/ https://ncbi.nlm.nih.gov/pubmed/27511871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.07.008 |
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