A ribonucleotide reductase inhibitor with deoxyribonucleoside‐reversible cytotoxicity

Ribonucleotide Reductase (RNR) is the sole enzyme that catalyzes the reduction of ribonucleotides into deoxyribonucleotides. Even though RNR is a recognized target for antiproliferative molecules, and the main target of the approved drug hydroxyurea, few new leads targeted to this enzyme have been d...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Oncol
Autores principales: Crona, Mikael, Codó, Paula, Jonna, Venkateswara Rao, Hofer, Anders, Fernandes, Aristi P., Tholander, Fredrik
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423217/
https://ncbi.nlm.nih.gov/pubmed/27511871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.07.008
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares