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Compounds with capacity to quench the tyrosyl radical in Pseudomonas aeruginosa ribonucleotide reductase

Ribonucleotide reductase (RNR) has been extensively probed as a target enzyme in the search for selective antibiotics. Here we report on the mechanism of inhibition of nine compounds, serving as representative examples of three different inhibitor classes previously identified by us to efficiently i...

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Dettagli Bibliografici
Pubblicato in:J Biol Inorg Chem
Autori principali: Berggren, Gustav, Sahlin, Margareta, Crona, Mikael, Tholander, Fredrik, Sjöberg, Britt-Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754346/
https://ncbi.nlm.nih.gov/pubmed/31218442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01679-w
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