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Compounds with capacity to quench the tyrosyl radical in Pseudomonas aeruginosa ribonucleotide reductase

Ribonucleotide reductase (RNR) has been extensively probed as a target enzyme in the search for selective antibiotics. Here we report on the mechanism of inhibition of nine compounds, serving as representative examples of three different inhibitor classes previously identified by us to efficiently i...

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Détails bibliographiques
Publié dans:J Biol Inorg Chem
Auteurs principaux: Berggren, Gustav, Sahlin, Margareta, Crona, Mikael, Tholander, Fredrik, Sjöberg, Britt-Marie
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754346/
https://ncbi.nlm.nih.gov/pubmed/31218442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01679-w
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