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Compounds with capacity to quench the tyrosyl radical in Pseudomonas aeruginosa ribonucleotide reductase

Ribonucleotide reductase (RNR) has been extensively probed as a target enzyme in the search for selective antibiotics. Here we report on the mechanism of inhibition of nine compounds, serving as representative examples of three different inhibitor classes previously identified by us to efficiently i...

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Detalles Bibliográficos
Publicado en:J Biol Inorg Chem
Autores principales: Berggren, Gustav, Sahlin, Margareta, Crona, Mikael, Tholander, Fredrik, Sjöberg, Britt-Marie
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754346/
https://ncbi.nlm.nih.gov/pubmed/31218442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01679-w
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