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Compounds with capacity to quench the tyrosyl radical in Pseudomonas aeruginosa ribonucleotide reductase

Ribonucleotide reductase (RNR) has been extensively probed as a target enzyme in the search for selective antibiotics. Here we report on the mechanism of inhibition of nine compounds, serving as representative examples of three different inhibitor classes previously identified by us to efficiently i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Inorg Chem
Egile Nagusiak: Berggren, Gustav, Sahlin, Margareta, Crona, Mikael, Tholander, Fredrik, Sjöberg, Britt-Marie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754346/
https://ncbi.nlm.nih.gov/pubmed/31218442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01679-w
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