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Compounds with capacity to quench the tyrosyl radical in Pseudomonas aeruginosa ribonucleotide reductase

Ribonucleotide reductase (RNR) has been extensively probed as a target enzyme in the search for selective antibiotics. Here we report on the mechanism of inhibition of nine compounds, serving as representative examples of three different inhibitor classes previously identified by us to efficiently i...

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Bibliografiska uppgifter
I publikationen:J Biol Inorg Chem
Huvudupphovsmän: Berggren, Gustav, Sahlin, Margareta, Crona, Mikael, Tholander, Fredrik, Sjöberg, Britt-Marie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754346/
https://ncbi.nlm.nih.gov/pubmed/31218442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01679-w
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